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beautybigbang posted a blog post

The Prerequisites for Genetic Analysis--De Novo Sequencing

A simple introduction of de novo sequencing The sequence was spliced and assembled by bioinformatics analysis to obtain the genome sequence map of the species. A species can be sequenced without any genetic information through this method. At present, de novo sequencing service is widely used to analyze the genome sequence, genetic composition and evolutionary characteristics of unknown…See More
Jun 24
beautybigbang posted a blog post

Preclinical toxicology study of new drugs

Definition of toxicologyToxicology is the science of studying the harmful effects of toxic substances on body and its mechanisms, outcomes, and hazards. It is mainly used for safety evaluation and risk assessment of exogenous substances.The tasks of drug toxicology include clinical toxicology, new drug clinical trials, and the task of drug epidemiology research. Its basic purpose is to understand and master the toxic effects of drugs, to provide a scientific basis for clinical safe medication…See More
Jun 21
beautybigbang posted a blog post

What is renal parenchymal hypertension?

What is renal parenchyma? The renal parenchyma can be divided into cortex and medulla, and the cortex is composed of glomeruli and curved tubules. The medulla is composed of 15 to 20 kidney vertebral bodies, and the tip of the kidney cone protrudes into the renal nipple, which is the opening of the nipple tube and the collecting tube. The renal pelvis is funnel-shaped, surrounding 1~3 kidney nipples, and every 2~3 kidneys are combined into one kidney sputum. Generally, the kidney has 3 large…See More
Jun 20
beautybigbang posted a blog post

Compare endothelial cells and epithelial cells and their differences

Endothelial cells cover the inner surface of the blood vessel, and epithelial cells cover the inner surface of the internal organs. The epithelial cells also cover the outer surface of the human body. If a large number of epithelial cells are found in the urine during urine testing, it indicates a urinary tract…See More
Jun 19
beautybigbang posted a blog post

Introduction to Transferase

Transferases are a class of enzymes that transfer specific functional groups from one molecule (donor) to another (acceptor). Transferases are implicated in hundreds of different biochemical pathways, and are essential to some of most important processes in lives. Transferases participate in a myriad of cell reactions and are also utilized during translation. Mechanistically, an enzyme catalyzing the following reaction…See More
Jun 17
beautybigbang posted a blog post

Biomarker: Active Pioneer in Medicine Fields

With the development of bioscience, biomarkers are widely used in medicine. Biomarkers are indicators that can judge the occurrence, development and prognosis of diseases. They can be used for the diagnosis and classification of diseases, monitoring the disease development and severity, testing the effect of clinical treatment, predicting an individual's risk of disease and the screening of high-risk groups. The selection of biomarkers requires strict clinical validation and the feasibility of…See More
Jun 13
beautybigbang posted a blog post

Wholesale Supply Chains in Business

Most merchants will testify to the fact that supply chains are often the most important factor in delivering products to their destination. Merchants that are capable of understanding this will reap all the benefits of an expanding market. If you can secure your own marketing model, then the supply chain will ensure that you do not run out of products to put out onto the market. Drop shipping is one of those areas where the supply chain will play a crucial part in the level of success that the…See More
Jun 10
beautybigbang posted blog posts
May 27
beautybigbang posted blog posts
May 23
beautybigbang posted a blog post

Guide for antibody selection and antibody application in cancers (part one)

Background introductionIn clinical biopsy, the correct judgment of various tumors has always been a critical issue for surgical pathology. It decides patient's treatment and prognosis. Before the immunohistochemical technique was carried out, HE was used to identify and diagnose various tumors. Although many problems were solved at the time, for more complicated and multi-type tumors, it is impossible to make a correct judgment about its origin. With the development of immunohistochemistry…See More
May 22
beautybigbang posted blog posts
May 21
beautybigbang posted a blog post

Researchers correct genetic mutation

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX. The gene therapy, which was tested in mice, is similar to the technique Kohn has used to cure patients with another immune disease, severe combined immune deficiency, or SCID, also known as bubble baby disease.The work is described in a study published in the journal Cell Stem Cell.IPEX is caused by a…See More
Apr 28
beautybigbang posted a blog post

Introduction to a protein engineering technique—mutation

Positional mutation is a protein engineering technique that substitutes, inserts or deletes specific nucleotides in known DNA sequences based on the known structure and function of proteins to produce mutant protein (enzyme) molecules with novel traits. The technology is widely used in the biological and medical fields. Position mutation technology has the characteristics of high mutation rate, simple and easy to perform, and good…See More
Apr 24
beautybigbang posted a blog post

Plant genetic engineering technology and its management

The genetic engineering was established in the early 1970s and it has played an important role in the field of biology after decades of continuous progress and development.Plant genetic engineering technology uses recombinant DNA technology to systematically transform and recombine biological genes by artificial "shearing" and "splicing" in vitro, and then insert and integrate into the recipient plant…See More
Apr 22
beautybigbang posted a blog post

Detailed introduction of protein structure

Protein is mainly composed of chemical elements such as carbon, hydrogen, oxygen and nitrogen. It is an important biological macromolecule. All proteins are multimers formed by the connection of 20 different amino acids. After Forming proteins, these amino acids are also called as a residue. The boundaries between proteins and peptides are not very clear. Some people believe that the number of residues required for a functionally acting domain is called a polypeptide or peptide if the number of…See More
Apr 19

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Beautybigbang's Blog

The Prerequisites for Genetic Analysis--De Novo Sequencing

Posted on June 24, 2019 at 3:16am 0 Comments

A simple introduction of de novo sequencing

 

The sequence was spliced and assembled by bioinformatics analysis to obtain the genome sequence map of the species. A species can be sequenced without any genetic information through this method. At present, de novo sequencing service is widely used to analyze the genome sequence, genetic…

Continue

Preclinical toxicology study of new drugs

Posted on June 21, 2019 at 3:36am 0 Comments

Definition of toxicology

Toxicology is the science of studying the harmful effects of toxic substances on body and its mechanisms, outcomes, and hazards. It is mainly used for safety evaluation and risk assessment of exogenous substances.

The tasks of drug toxicology include clinical toxicology, new drug clinical trials, and the task of drug epidemiology research. Its basic purpose is to understand and master the toxic effects of drugs, to provide a…

Continue

What is renal parenchymal hypertension?

Posted on June 20, 2019 at 3:14am 0 Comments

What is renal parenchyma? The renal parenchyma can be divided into cortex and medulla, and the cortex is composed of glomeruli and curved tubules. The medulla is composed of 15 to 20 kidney vertebral bodies, and the tip of the kidney cone protrudes into the renal nipple, which is the opening of the nipple tube and the collecting tube. The renal pelvis is funnel-shaped, surrounding 1~3 kidney nipples, and every 2~3 kidneys are combined into one kidney sputum. Generally, the kidney has 3 large…

Continue

Compare endothelial cells and epithelial cells and their differences

Posted on June 19, 2019 at 1:52am 0 Comments

Endothelial cells cover the inner surface of the blood vessel, and epithelial cells cover the inner surface of the internal organs. The epithelial cells also cover the outer surface of the human body. If a large number of epithelial cells are found in the urine during urine testing, it indicates a…

Continue

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